tert-butyl ((1S)-3-(3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)carbamate -Drug Synthesis Database

【结构式】

【分子编号】67270

【品名】tert-butyl ((1S)-3-(3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)carbamate

【CA登记号】　

【分子式】C₂₇H₄₁N₅O₂

【分子量】467.655

【元素组成】C 69.35% H 8.84% N 14.98% O 6.84%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(V)

【1】 Price DA, Gayton S, Selby MD, et al. 2005. Initial synthesis of UK-427, 857(maraviroc). Tetrahedron Letters, 46(30): 5005～5007.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(III)	67269	(S)-tert-butyl (3-oxo-1-phenylpropyl)carbamate	135865-78-0	C₁₄H₁₉NO₃	详情	详情
(VI)	67261	(1S)-3-(3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropan-1-amine		C₂₂H₃₃N₅	详情	详情
(I)	67267	methyl 3-amino-3-phenylpropanoate		C₁₀H₁₃NO₂	详情	详情
(II)	67268	(S)-methyl 3-((tert-butoxycarbonyl)amino)-3-phenylpropanoate		C₁₅H₂₁NO₄	详情	详情
(IV)	10498	Benzaldehyde;Benzoic aldehyde;Phenylmethanal	100-52-7	C₇H₆O	详情	详情
(V)	67270	tert-butyl ((1S)-3-(3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl)-1-phenylpropyl)carbamate		C₂₇H₄₁N₅O₂	详情	详情
(VII)	67271	4,4-difluorocyclohexanecarboxylic acid	122665-97-8	C₇H₁₀F₂O₂	详情	详情

Extended Information