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【结 构 式】 
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【分子编号】67212 【品名】benzyl (2-(methylsulfonyl)ethyl)carbamate 【CA登记号】 |
【 分 子 式 】C11H15NO4S 【 分 子 量 】257.31 【元素组成】C 51.35% H 5.87% N 5.44% O 24.87% S 14.46% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(III)
| 【1】 Petrov KG, Zhang YM, Carter M, et al. 2006. Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series. Bioorganic & Medicinal Chemistry Letters, 16, 4686～4691. |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 11240 | 2-(Methylsulfanyl)ethylamine; 2-(Methylthio)ethylamine; 2-(Methylsulfanyl)-1-ethanamine | 18542-42-2 | C3H9NS | 详情 | 详情 |
| (II) | 67211 | benzyl (2-(methylthio)ethyl)carbamate | C11H15NO2S | 详情 | 详情 | |
| (III) | 67212 | benzyl (2-(methylsulfonyl)ethyl)carbamate | C11H15NO4S | 详情 | 详情 | |
| (IV) | 49880 | 2-(methylsulfonyl)-1-ethanamine; 2-(methylsulfonyl)ethylamine | C3H9NO2S | 详情 | 详情 | |
| (VI) | 49872 | 1-Chloro-2-Hydroxy-5-Nitrobenzene; 2-Chloro-4-nitrophenol; 4-Nitro-2-chlorophenol; p-Nitro-o-chlorophenol | 619-08-9 | C6H4ClNO3 | 详情 | 详情 |
| (VII) | 17221 | 3-Fluorobenzyl bromide; 1-(bromomethyl)-3-fluorobenzene | 456-41-7 | C7H6BrF | 详情 | 详情 |
| (VIII) | 49873 | 2-chloro-1-[(3-fluorobenzyl)oxy]-4-nitrobenzene; 2-chloro-4-nitrophenyl 3-fluorobenzyl ether | C13H9ClFNO3 | 详情 | 详情 | |
| (IX) | 49874 | 3-chloro-4-[(3-fluorobenzyl)oxy]phenylamine; 3-chloro-4-[(3-fluorobenzyl)oxy]aniline | C13H11ClFNO | 详情 | 详情 | |
| (X) | 49875 | 4-chloro-6-iodoquinazoline | 98556-31-1 | C8H4ClIN2 | 详情 | 详情 |
| (XI) | 49876 | N-[3-chloro-4-[(3-fluorobenzyl)oxy]phenyl]-N-(6-iodo-4-quinazolinyl)amine; N-[3-chloro-4-[(3-fluorobenzyl)oxy]phenyl]-6-iodo-4-quinazolinamine | C21H14ClFIN3O | 详情 | 详情 | |
| (XII) | 67214 | (5-formylfuran-2-yl)boronic acid | 27329-70-0 | C5H5BO4 | 详情 | 详情 |
| (XIII) | 49879 | 5-(4-[3-chloro-4-[(3-fluorobenzyl)oxy]anilino]-6-quinazolinyl)-2-furaldehyde | C26H17ClFN3O3 | 详情 | 详情 |
Extended Information