4-nitrobenzyl 4-(acetylthio)-2-(((((4-nitrobenzyl)oxy)carbonyl)(sulfamoyl)amino)methyl)pyrrolidine-1-carboxylate -Drug Synthesis Database

【结构式】

【分子编号】67096

【品名】4-nitrobenzyl 4-(acetylthio)-2-(((((4-nitrobenzyl)oxy)carbonyl)(sulfamoyl)amino)methyl)pyrrolidine-1-carboxylate

【CA登记号】　

【分子式】C₂₃H₂₅N₅O₁₁S₂

【分子量】611.611

【元素组成】C 45.17% H 4.12% N 11.45% O 28.77% S 10.49%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(IV)

【1】 Xu DY, Tang Y, Zhou WC, et al.2007. Preparation of pyrrolidine derivatives as doripenem intermediates. CN 1896057 A.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	67093	4-Nitrobenzyl alcohol;p-Nitrobenzyl alcohol	619-73-8	C₇H₇NO₃	详情	详情
(II)	67094	4-nitrobenzyl 2-sulfamoylacetate		C₉H₁₀N₂O₆S	详情	详情
(III)	67095	4-nitrobenzyl 4-(acetylthio)-2-(hydroxymethyl)pyrrolidine-1-carboxylate		C₁₅H₁₈N₂O₆S	详情	详情
(IV)	67096	4-nitrobenzyl 4-(acetylthio)-2-(((((4-nitrobenzyl)oxy)carbonyl)(sulfamoyl)amino)methyl)pyrrolidine-1-carboxylate		C₂₃H₂₅N₅O₁₁S₂	详情	详情
(V)	67097	4-nitrobenzyl 4-mercapto-2-(((((4-nitrobenzyl)oxy)carbonyl)(sulfamoyl)amino)methyl)pyrrolidine-1-carboxylate		C₂₁H₂₃N₅O₁₀S₂	详情	详情
(VI)	16100	benzhydryl (4R,5R,6S)-3-[(diphenoxyphosphoryl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate		C₃₅H₃₂NO₈P	详情	详情
(VII)	67098	nitro(phenyl)methyl 6-(1-hydroxyethyl)-4-methyl-3-((1-(((4-nitrobenzyl)oxy)carbonyl)-5-(((((4-nitrobenzyl)oxy)carbonyl)(sulfamoyl)amino)methyl)pyrrolidin-3-yl)thio)-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate		C₃₈H₃₉N₇O₁₆S₂	详情	详情

Extended Information