3-((4S,4aR,7S,8R)-4,7-dimethyl-4,4a,5,6,7,8-hexahydro-3H-isochromen-8-yl)propanoic acid -Drug Synthesis Database

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【结构式】

【分子编号】67031

【品名】3-((4S,4aR,7S,8R)-4,7-dimethyl-4,4a,5,6,7,8-hexahydro-3H-isochromen-8-yl)propanoic acid

【CA登记号】　

【分子式】C₁₄H₂₂O₃

【分子量】 238.32688

【元素组成】C 70.56% H 9.3% O 20.14%

与该中间体有关的原料药合成路线共 1 条

合成路线1

合成路线1

该中间体在本合成路线中的序号：(XV)

　

参考文献中间体

【1】 Deshpande VH, Bhonsle JB, Pandey B, et al. 1994. New synthesis strategies towards(+) -artemisinin. Tetrahedron Lett, 35(30):5489～5492.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	10208	L-Menthone; (2S,5R)-2-Isopropyl-5-methylcyclohexanone	14073-97-3	C₁₀H₁₈O	详情	详情
(II)	10209	(3R,6S)-2-[(Dimethylamino)methyl]-6-isopropyl-3-methylcyclohexanone		C₁₃H₂₅NO	详情	详情
(III)	10210	(4aS,5R,8S)-8-Isopropyl-5-methyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone		C₁₄H₂₂O	详情	详情
(IV)	10211	(1aS,4aS,5R,8S,8aS)-8-Isopropyl-5-methylhexahydro-1aH-naphtho[1,8a-b]oxiren-2(3H)-one		C₁₄H₂₂O₂	详情	详情
(V)	10212	(2S,4aS,5R,8S)-8-Isopropyl-5-methyloctahydro-2,8a(1H)-naphthalenediol		C₁₄H₂₆O₂	详情	详情
(VI)	10213	(2S,4aS,5R,8S,8aS)-8a-Hydroxy-8-isopropyl-5-methyldecahydro-2-naphthalenyl acetate		C₁₆H₂₈O₃	详情	详情
(VII)	67030	(3aS,6R,6aS,9S,10aR)-3,6-Dimethyldecahydro-2H-naphtho[8a,1-b]furan-9-ol		C₁₄H₂₄O₂	详情	详情
(VIII)	10215	(3aS,6R,6aS,10aR)-3,6-Dimethyloctahydro-2H-naphtho[8a,1-b]furan-9(10H)-one		C₁₄H₂₂O₂	详情	详情
(IX)	10216	(4aS,5R,8S)-8-(2-Hydroxy-1-methylethyl)-5-methyl-4,4a,5,6,7,8-hexahydro-2(3H)-naphthalenone		C₁₄H₂₂O₂	详情	详情
(X)	10217	(4aS,5R,8R,8aS)-8-(2-Hydroxy-1-methylethyl)-5-methyloctahydro-2(1H)-naphthalenone		C₁₄H₂₄O₂	详情	详情
(XI)	10218	(4aS,5R,8R,8aS)-8-(2-Hydroxy-1-methylethyl)-2,5-dimethyldecahydro-2-naphthalenol		C₁₅H₂₈O₂	详情	详情
(XII)	10219	2-[(1R,4R,4aS,8aS)-7-hydroxy-4,7-dimethyldecahydro-1-naphthalenyl]propyl acetate		C₁₇H₃₀O₃	详情	详情
(XIII)	10220	2-[(1R,4R,4aS,8aS)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydro-1-naphthalenyl]propyl acetate		C₁₇H₂₈O₂	详情	详情
(XIV)	10221	2-[(1R,4R,4aS,8aS)-4,7-Dimethyl-1,2,3,4,4a,5,6,8a-octahydro-1-naphthalenyl]-1-propanol		C₁₅H₂₆O	详情	详情
(XV)	67031	3-((4S,4aR,7S,8R)-4,7-dimethyl-4,4a,5,6,7,8-hexahydro-3H-isochromen-8-yl)propanoic acid		C₁₄H₂₂O₃	详情	详情
(XVI)	10224	(1R,4S,5R,8S,9R,12R,13R)-1,5,9-Trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0(4,13).0(8,13)]hexadecane		C₁₅H₂₄O₄	详情	详情

Extended Information