dimethyl 2-((2E,4E,6E,8Z)-6-methyl-8-(2,6,6-trimethylcyclohex-2-en-1-ylidene)octa-2,4,6-trien-2-yl)malonate -Drug Synthesis Database

【结构式】

【分子编号】66904

【品名】dimethyl 2-((2E,4E,6E,8Z)-6-methyl-8-(2,6,6-trimethylcyclohex-2-en-1-ylidene)octa-2,4,6-trien-2-yl)malonate

【CA登记号】　

【分子式】C₂₃H₃₂O₄

【分子量】372.50468

【元素组成】C 74.16% H 8.66% O 17.18%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号： (V)

【1】 Cartier D, Valla A, Le Guillou R, et al. 2003. New, regiaselective, one-pot synthesis of (all-E) -retinoic acid and analogues from enaminodiester synthons. Eur J Org Chem, (12). 2250～2253
【2】 Cartier D, Valla A, Labia R, et al. 2003. A new one-pot synthesis of all E-retinoic acid via a new enamin odiester synthon. Tetrahedrcm Lett, 44 (31): 5789～5790

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	49671	dimethyl 2-(1-methylethylidene)malonate	22035-53-6	C₈H₁₂O₄	详情	详情
(V)	66904	dimethyl 2-((2E,4E,6E,8Z)-6-methyl-8-(2,6,6-trimethylcyclohex-2-en-1-ylidene)octa-2,4,6-trien-2-yl)malonate		C₂₃H₃₂O₄	详情	详情
(II)	66902	(E)-dimethyl 2-(4-(dimethylamino)but-3-en-2-ylidene)malonate		C₁₁H₁₇NO₄	详情	详情
(III)	39584	(E)-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-buten-2-one	14901-07-6	C₁₃H₂₀O	详情	详情
(IV)	66903	dimethyl 2-((2E,4E,7E)-6-oxo-8-(2,6,6-trimethylcyclohex-1-en-1-yl)octa-2,4,7-trien-2-yl)malonate		C₂₂H₃₀O₅	详情	详情

Extended Information