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【结 构 式】 
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【分子编号】66875 【品名】3-(1-(3-(dibenzylamino)phenyl)propyl)-4-hydroxy-6,6-dipropyl-5,6-dihydro-2H-pyran-2-one 【CA登记号】 |
【 分 子 式 】C34H41NO3 【 分 子 量 】511.704 【元素组成】C 79.81% H 8.08% N 2.74% O 9.38% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(XII)
| 【1】 Judge TM, Phillips G, Moms JK, et aL. 1997. A symmetric syntheses and absolute stereochemistry of 5,6-dihydro-α-pyrones, a new class of potent HIV proteese inhibitors. J Am Chem Soc, 119 (15): 3627～3628 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 12173 | (4S)-4-Phenyl-1,3-oxazolan-2-one; (4S)-4-Phenyl-2-oxazolidinone; (S)-(+)-4-Phenyl-2-oxazolidinone | 99395-88-7 | C9H9NO2 | 详情 | 详情 |
| (II) | 17227 | (4R)-3-[(E)-2-pentenoyl]-4-phenyl-1,3-oxazolan-2-one | C14H15NO3 | 详情 | 详情 | |
| (III) | 17228 | N-(3-methylphenyl)-N,N-bis(trimethylsilyl)amine; trimethyl-N-(3-methylphenyl)-N-(trimethylsilyl)silanamine | C13H25NSi2 | 详情 | 详情 | |
| (V) | 17231 | 2-methoxy-2-methyl-1,3-dioxolane; methyl 2-methyl-1,3-dioxolan-2-yl ether | C5H10O3 | 详情 | 详情 | |
| (VI) | 17232 | (2S)-2-[(1S)-1-[3-(dibenzylamino)phenyl]propyl]-1-[(4R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-1,3-butanedione | C36H36N2O4 | 详情 | 详情 | |
| (XI) | 66877 | 2-(1-(3-(dibenzylamino)phenyl)propyl)-5-hydroxy-1-(2-oxo-4-phenyloxazolidin-3-yl)-5-phenethyloctane-1,3-dione | C48H52N2O5 | 详情 | 详情 | |
| (IV) | 17229 | (4R)-3-((3S)-3-[3-[bis(trimethylsilyl)amino]phenyl]pentanoyl)-4-phenyl-1,3-oxazolan-2-one | C26H38N2O3Si2 | 详情 | 详情 | |
| (VII) | 10385 | 4-Heptanone; Dipropyl ketone | 123-19-3 | C7H14O | 详情 | 详情 |
| (VIII) | 17233 | 1-phenyl-3-hexanone | C12H16O | 详情 | 详情 | |
| (IX) | 66878 | 2-(1-(3-(dibenzylamino)phenyl)propyl)-5-hydroxy-1-(2-oxo-4-phenyloxazolidin-3-yl)-5-propyloctane-1,3-dione | C43H50N2O5 | 详情 | 详情 | |
| (X) | 17234 | (2S,5R)-2-[(1S)-1-[3-(dibenzylamino)phenyl]propyl]-5-hydroxy-1-[(4R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-5-phenethyl-1,3-octanedione | C48H52N2O5 | 详情 | 详情 | |
| (XII) | 66875 | 3-(1-(3-(dibenzylamino)phenyl)propyl)-4-hydroxy-6,6-dipropyl-5,6-dihydro-2H-pyran-2-one | C34H41NO3 | 详情 | 详情 | |
| (XIII) | 17235 | (6R)-3-[(1R)-1-[3-(dibenzylamino)phenyl]propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one | C39H43NO3 | 详情 | 详情 | |
| (XIV) | 66876 | N-(3-(1-(4-hydroxy-2-oxo-6,6-dipropyl-5,6-dihydro-2H-pyran-3-yl)propyl)phenyl)-5-(trifluoromethyl)pyridine-2-sulfonamide | C26H31F3N2O5S | 详情 | 详情 | |
| (XVI) | 17238 | 1-phenyl-4-hexyn-3-one | C12H12O | 详情 | 详情 | |
| (XVII) | 17239 | (2S,5R)-2-[(1S)-1-[3-(dibenzylamino)phenyl]propyl]-5-hydroxy-1-[(4R)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-5-phenethyl-6-octyne-1,3-dione | C48H48N2O5 | 详情 | 详情 | |
| (XVIII) | 17240 | (6R)-3-[(1R)-1-[3-(dibenzylamino)phenyl]propyl]-4-hydroxy-6-phenethyl-6-(1-propynyl)-5,6-dihydro-2H-pyran-2-one | C39H39NO3 | 详情 | 详情 | |
| (XIX) | 17236 | (6R)-3-[(1R)-1-(3-aminophenyl)propyl]-4-hydroxy-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-2-one | C25H31NO3 | 详情 | 详情 |
Extended Information