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【结 构 式】 
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【分子编号】66831 【品名】(2S)-ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)propanoate 【CA登记号】73208-70-5 |
【 分 子 式 】C10H18O4 【 分 子 量 】202.25052 【元素组成】C 59.39% H 8.97% O 31.64% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)
| 【1】 Holy A, Dvorakovs H, Declercq ED, et al. Preparation of antiretroviral enantiomeric nucleotide analogs. WO 9403467 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 66830 | (S)-ethyl 2-hydroxypropanoate | C5H10O3 | 详情 | 详情 | |
| (II) | 66831 | (2S)-ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)propanoate | 73208-70-5 | C10H18O4 | 详情 | 详情 |
| (III) | 19228 | (2S)-2-(tetrahydro-2H-pyran-2-yloxy)-1-propanol | 76946-21-9 | C8H16O3 | 详情 | 详情 |
| (IV) | 19229 | (2S)-2-(tetrahydro-2H-pyran-2-yloxy)propyl 4-methylbenzenesulfonate | C15H22O5S | 详情 | 详情 | |
| (V) | 10343 | 9H-Purin-6-amine; 9H-Purin-6-ylamine; Adenine | 73-24-5 | C5H5N5 | 详情 | 详情 |
| (VI) | 19231 | 9-[(2S)-2-(tetrahydro-2H-pyran-2-yloxy)propyl]-9H-purin-6-amine; 9-[(2R)-2-(tetrahydro-2H-pyran-2-yloxy)propyl]-9H-purin-6-ylamine | C13H19N5O2 | 详情 | 详情 | |
| (VII) | 19232 | (2S)-1-(6-amino-9H-purin-9-yl)-2-propanol | C8H11N5O | 详情 | 详情 | |
| (VIII) | 19233 | N-[9-[(2S)-2-hydroxypropyl]-9H-purin-6-yl]benzamide | C15H15N5O2 | 详情 | 详情 | |
| (IX) | 19234 | (diisopropoxyphosphoryl)methyl 4-methylbenzenesulfonate | C14H23O6PS | 详情 | 详情 | |
| (X) | 19246 | diethyl [[(1S)-2-(6-amino-9H-purin-9-yl)-1-methylethyl]oxy]methylphosphonate | C13H22N5O4P | 详情 | 详情 |
Extended Information