(5R)-5-((benzyloxy)methyl)tetrahydrofuran-2,4-diol -Drug Synthesis Database

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【结构式】

【分子编号】66799

【品名】(5R)-5-((benzyloxy)methyl)tetrahydrofuran-2,4-diol

【CA登记号】　

【分子式】C₁₂H₁₆O₄

【分子量】224.25664

【元素组成】C 64.27% H 7.19% O 28.54%

与该中间体有关的原料药合成路线共 1 条

合成路线1

合成路线1

该中间体在本合成路线中的序号：(VI)

　

参考文献中间体

【1】 Storer R. Moussa A. Wang JY. et al. 2005. Synthesis of β-L-2-deoxy-nucleosides from furanoses and pyranoses via a chloro-sugar and anhydro-l-furanosyl-nucleobase intennediatcs as potential antiviral and antineoplastic agents. W0 2005003374

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
（X）	12204	5-Methyl-2,4(1H,3H)-pyrimidinedione; Thymine	65-71-4	C₅H₆N₂O₂	详情	详情
(I)	11471	1,4-Pentadien-3-ol	922-65-6	C₅H₈O	详情	详情
(II)	66795	(S)-1-((S)-oxiran-2-yl)prop-2-en-1-ol		C₅H₈O₂	详情	详情
(III)	66796	(2R,3S)-1-(benzyloxy)pent-4-ene-2,3-diol		C₁₂H₁₆O₃	详情	详情
(IV)	66797			C₁₅H₂₀O₃	详情	详情
(V)	66798	2-((4R,5R)-5-((benzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)acetaldehyde		C₁₅H₂₀O₄	详情	详情
(VI)	66799	(5R)-5-((benzyloxy)methyl)tetrahydrofuran-2,4-diol		C₁₂H₁₆O₄	详情	详情
(VII)	66800	(2R)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran-3-ol		C₁₃H₁₈O₄	详情	详情
(VIII)	12241	(2R,3S)-2-(Hydroxymethyl)-5-methoxytetrahydro-3-furanol		C₆H₁₂O₄	详情	详情
(IX)	37194	(2R,3S)-5-Chloro-2-[[(4-methylbenzoyl)oxy]methyl]tetrahydro-3-furanyl 4-methylbenzoate	4330-21-6	C₂₁H₂₁ClO₅	详情	详情
(XIV)	62918	{(2S,3R,5S)-3-[(4-methylbenzoyl)oxy]-5-[5-methyl-2,4-dioxo-3,4-dihydro-1(2H)-pyrimidinyl]tetrahydro-2-furanyl}methyl 4-methylbenzoate		C₂₆H₂₆N₂O₇	详情	详情

Extended Information