5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzyl)thiazolidine-2,4-dione -Drug Synthesis Database

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【结构式】

【分子编号】66595

【品名】5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzyl)thiazolidine-2,4-dione

【CA登记号】　

【分子式】C₁₉H₂₀N₂O₄S

【分子量】372.44488

【元素组成】C 61.27% H 5.41% N 7.52% O 17.18% S 8.61%

与该中间体有关的原料药合成路线共 1 条

合成路线1

合成路线1

该中间体在本合成路线中的序号：(VI)

　

参考文献中间体

【1】 Pandey B, Lohray VB, Lohray BB, 2004. A novel process to prepare pioglitazone via several intermediates. W0 200400749
【2】 Pandey B,Lohray VB, Lohray BB. 2006. Novel process to prepare pioglitazone via several novel intermediates. US 20060167061

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	66590	5-ethyl-2-vinylpyridine	5408-74-2	C₉H₁₁N	详情	详情
(II)	66591	2-bromo-1-(5-ethylpyridin-2-yl)ethanol	646519-81-5	C₉H₁₂BrNO	详情	详情
(III)	66592	5-ethyl-2-(oxiran-2-yl)pyridine		C₉H₁₁NO	详情	详情
(IV)	66593	4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzaldehyde		C₁₆H₁₇NO₃	详情	详情
(V)	66594	(E)-5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzylidene)thiazolidine-2,4-dione		C₁₉H₁₈N₂O₄S	详情	详情
(VI)	66595	5-(4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzyl)thiazolidine-2,4-dione		C₁₉H₂₀N₂O₄S	详情	详情
(VII)	66596	5-(4-(2-chloro-2-(5-ethylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione		C₁₉H₁₉ClN₂O₃S	详情	详情

Extended Information