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【结 构 式】 
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【分子编号】66557 【品名】1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid 【CA登记号】144689-24-7 |
【 分 子 式 】C24H26N6O3 【 分 子 量 】446.509 【元素组成】C 64.60% H 5.87% N 18.82% O 10.75% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(VI)
| 【1】 Hedvati L.Pilarsky G, Shenkar-Garcia N.2006. Process for preparing olmesartan medoxomil at pH higher than 2.5.US 20060148870 |
| 【2】 Hedvati L,Pilarsky G-2006. Prooess for the preparation of olmesartan medoxomiL. W0 2006029056（本专利属于Teva Pharmaceutical Industries Ltd.Israeli Teva Phumaceuticals Usa Inc) |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 16906 | diethyl 2-propyl-1H-imidazole-4,5-dicarboxylate | C12H18N2O4 | 详情 | 详情 | |
| (II) | 16907 | ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1H-imidazole-5-carboxylate | C12H20N2O3 | 详情 | 详情 | |
| (III) | 15332 | 4'-(bromomethyl)[1,1'-biphenyl]-2-carbonitrile; 4'-bromomethyl-2-cyanobiphenyl | 114772-54-2 | C14H10BrN | 详情 | 详情 |
| (IV) | 16919 | ethyl 1-[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]-4-(1-hydroxy-1-methylethyl)-2-propyl-1H-imidazole-5-carboxylate | C26H29N3O3 | 详情 | 详情 | |
| (V) | 16920 | ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(1H-1,2,3,4-tetraazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate | C26H30N6O3 | 详情 | 详情 | |
| (VI) | 66557 | 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylic acid | 144689-24-7 | C24H26N6O3 | 详情 | 详情 |
Extended Information