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【结 构 式】 
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【分子编号】66451 【品名】tert-butyl 3-(aminomethylene)-4-oxopyrrolidine-1-carboxylate 【CA登记号】 |
【 分 子 式 】C10H16N2O3 【 分 子 量 】212.24872 【元素组成】C 56.59% H 7.6% N 13.2% O 22.61% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)
| 【1】 Hong CY, Kim YK, Chang JH, et aL 1997. Novel fluoroquinolone antibacterial agents containing oximesubstituted (aminomethyl) pyrrolidines: synthesis ancl antibacterial activity of 7-[4-(aminomethyl)-3-(methox}rimino) pyrrolidin-l-yl]-l-cyclopropyl-6-fluoro-4-axa-l, 4-dihydro[1,8]naphthyridine-3-carboxylic acid (LB20304).J Med Chem, 40 (22): 3584~3593 |
| 【2】 Kwak JH. 1997. Novel quinoline carboxylic acid derivatives having 7-(4-anuno-methyl-3-oxime) pyrrolidine substituents and processes for their preparation. US 5698570【本专利为LG Chm Ltd所有） |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (IV) | 17735 | tert-butyl 3-[[(tert-butoxycarbonyl)amino]methyl]-4-oxo-1-pyrrolidinecarboxylate | C15H26N2O5 | 详情 | 详情 | |
| (I) | 17732 | tert-butyl 3-cyano-4-oxo-1-pyrrolidinecarboxylate | C10H14N2O3 | 详情 | 详情 | |
| (II) | 66451 | tert-butyl 3-(aminomethylene)-4-oxopyrrolidine-1-carboxylate | C10H16N2O3 | 详情 | 详情 | |
| (III) | 66452 | tert-butyl 3-(((tert-butoxycarbonyl)amino)methylene)-4-oxopyrrolidine-1-carboxylate | C15H24N2O5 | 详情 | 详情 | |
| (V) | 17737 | tert-butyl 3-[[(tert-butoxycarbonyl)amino]methyl]-4-(methoxyimino)-1-pyrrolidinecarboxylate | C16H29N3O5 | 详情 | 详情 | |
| (VI) | 17738 | 4-(aminomethyl)-3-pyrrolidinone O-methyloxime | C6H13N3O | 详情 | 详情 |
Extended Information