【结 构 式】 |
【分子编号】66446 【品名】7-methoxy-4-oxo-1,4-dihydroquinazolin-6-yl acetate 【CA登记号】 |
【 分 子 式 】C11H10N2O4 【 分 子 量 】234.21148 【元素组成】C 56.41% H 4.3% N 11.96% O 27.32% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号:(II)
【1】 Knesl P.Roeseling D,Jordis U 2006. Improved synthesis of substituted 6,7-rdihydroxy-4iuinazolinearninest: tandutinib, erlotinib and gefitinib. Molecules, 11(4):286~297 |
中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
---|---|---|---|---|---|---|
(I) | 65853 | 5-Hydroxy-7-methoxy-3,4-dihydroquinazolin-4-one; 5-Hydroxy-7-methoxy-3H-quinazolin-4-one | C9H8N2O3 | 详情 | 详情 | |
(II) | 66446 | 7-methoxy-4-oxo-1,4-dihydroquinazolin-6-yl acetate | C11H10N2O4 | 详情 | 详情 | |
(III) | 18687 | 4-chloro-7-methoxy-6-quinazolinyl acetate | 230955-75-6 | C11H9ClN2O3 | 详情 | 详情 |
(IV) | 18688 | 3-Chloro-4-fluorophenylamine; 3-Chloro-4-fluoroaniline | 367-21-5 | C6H5ClFN | 详情 | 详情 |
(V) | 66447 | 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate hydrochloride;6-Acetoxy-4-(3-chloro-4-fluoroanilino)-7-methoxyquinazoline hydrochloride | 184475-70-5 | C17H13ClFN3O3.HCl | 详情 | 详情 |
(VI) | 18690 | 4-(3-chloro-4-fluoroanilino)-7-methoxy-6-quinazolinol | 184475-71-6 | C15H11ClFN3O2 | 详情 | 详情 |
(VII) | 18691 | 4-(3-chloropropyl)morpholine;N-(3-Chloropropyl)morpholine | 7357-67-7 | C7H14ClNO | 详情 | 详情 |
Extended Information