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【结 构 式】 
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【分子编号】66348 【品名】N-(6-((3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)-2,2,2-trifluoroacetamide 【CA登记号】 |
【 分 子 式 】C29H28F3NO11 【 分 子 量 】623.53667 【元素组成】C 55.86% H 4.53% F 9.14% N 2.25% O 28.23% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(III)
| 【1】 Matvienko V, Matvyeyev A, et aL 2006. Epimerization of 4'-C bond and modification of 14-Me(CO)-fragment in anthracyclin antibiotics. W0 2006096665 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 66341 | (8S,10S)-8-acetyl-10-((4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride | C27H29NO10.HCl | 详情 | 详情 | |
| (II) | 66347 | 6-((3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-2-methyl-4-(2,2,2-trifluoroacetamido)tetrahydro-2H-pyran-3-yl 2,2,2-trifluoroacetate | C31H27F6NO12 | 详情 | 详情 | |
| (III) | 66348 | N-(6-((3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)-2,2,2-trifluoroacetamide | C29H28F3NO11 | 详情 | 详情 | |
| (IV) | 66349 | N-(6-((3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-2-methyl-3-oxotetrahydro-2H-pyran-4-yl)-2,2,2-trifluoroacetamide | C29H26F3NO11 | 详情 | 详情 | |
| (V) | 66350 | N-(6-((3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl)oxy)-3-hydroxy-2-methyltetrahydro-2H-pyran-4-yl)-2,2,2-trifluoroacetamide | C29H28F3NO11 | 详情 | 详情 | |
| (VI) | 66351 | C27H29NO10.HCl | 详情 | 详情 |
Extended Information