2-cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylamide -Drug Synthesis Database

【结构式】

【分子编号】66318

【品名】2-cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylamide

【CA登记号】　

【分子式】C₁₅H₁₇N₃O₅

【分子量】319.3172

【元素组成】C 56.42% H 5.37% N 13.16% O 25.05%

与该中间体有关的原料药合成路线共 2 条

该中间体在本合成路线中的序号：(III)

【1】 Jasti V.Veera Reddy A, et aL 2005. Catalytic aldol condensation and acid hydrolysis process for the preparation of cntacapone from 3-alkoxy4-hydroxy-5-nitrobenzadehyde ruul N, N-diethyl-2-cyanoacetamide. W0 2005063693

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	66317	5-Nitrovanillin;4-Hydroxy-3-methoxy-5-nitrobenzaldehyde	6635-20-7	C₈H₇NO₅	详情	详情
(II)	15283	2-cyano-N,N-diethylacetamide	26391-06-0	C₇H₁₂N₂O	详情	详情
(III)	66318	2-cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylamide		C₁₅H₁₇N₃O₅	详情	详情

该中间体在本合成路线中的序号：(IV)

【1】 Cziaky Z 2006.Process for the preparation of entacapone in a stable polymorphic form and preparation of intermediates for its preparation. W0 2006064296

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	22701	4-hydroxy-3-methoxybenzaldehyde	121-33-5	C₈H₈O₃	详情	详情
(II)	15283	2-cyano-N,N-diethylacetamide	26391-06-0	C₇H₁₂N₂O	详情	详情
(III)	66319	2-cyano-N,N-diethyl-3-(4-hydroxy-3-methoxyphenyl)acrylamide		C₁₅H₁₈N₂O₃	详情	详情
(IV)	66318	2-cyano-N,N-diethyl-3-(4-hydroxy-3-methoxy-5-nitrophenyl)acrylamide		C₁₅H₁₇N₃O₅	详情	详情

Extended Information