|
【结 构 式】 
|
【分子编号】61244 【品名】(2R)-2-(2-methoxy-2-oxoethyl)hexanoic acid 【CA登记号】 |
【 分 子 式 】C9H16O4 【 分 子 量 】188.22364 【元素组成】C 57.43% H 8.57% O 34% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)In an alternative procedure, (R)-2-butylsuccinic acid 4-methyl ester (I) is coupled to L-proline tert-butyl ester (II) to afford amide (III). Then, displacement of the methyl ester group with hydroxylamine gives rise to the desired hydroxamic acid.
| 【1】 Jacobs, J.W.; Yuan, Z.; Ni, Z.-J.; Jain, R.; Patel, D.; Novel succinate cpds., compsns. and methods of use and preparation. US 2002115863 . |
Extended Information