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【结 构 式】 
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【分子编号】59334 【品名】N~1~,N~3~-bis(2,3-dihydroxypropyl)-5-{2-[(2-hydroxyethyl)amino]-2-oxoethoxy}-2,4,6-triiodoisophthalamide 【CA登记号】 |
【 分 子 式 】C18H24I3N3O9 【 分 子 量 】807.11679 【元素组成】C 26.79% H 3% I 47.17% N 5.21% O 17.84% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)In a different strategy, the target N-aryl hydroxy acetamide has been obtained by Smiles rearrangement of the aryloxy acetamide (I) under basic conditions.
| 【1】 Anelli, P.L.; et al.; Smiles rearrangement as a tool for the preparation of 5-[(2-hydroxyacyl)amino]-2,4,6-triiodo-1,3-benzenedicarboxamides: Main pathway and side reactions. Tetrahedron 1997, 53, 34, 11919. |
| 【2】 Musu, C.; Felder, E.; Fumagalli, L.; Piva, R.; Uggeri, F.; Smiles rearrangement, a new synthetic pathway to the synthesis of 5-(hydroxyacyl)-amino-2,4,6-triiodoisophthalamides. Invest Radiol 1990, 25, Suppl. 1, S100-1. |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 59334 | N~1~,N~3~-bis(2,3-dihydroxypropyl)-5-{2-[(2-hydroxyethyl)amino]-2-oxoethoxy}-2,4,6-triiodoisophthalamide | C18H24I3N3O9 | 详情 | 详情 |
Extended Information