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【结 构 式】 
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【分子编号】58659 【品名】1,3-diethyl-2-[7,12,17-tris(1,3-diethyl-1H-imidazol-3-ium-2-yl)-21,22,23,24-tetraazapentacyclo[16.2.1.1~3,6~.1~8,11~.1~13,16~]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaen-2-yl]-1H-imidazol-3-ium tetraiodide 【CA登记号】 |
【 分 子 式 】C48H58I4N12 【 分 子 量 】1310.68728 【元素组成】C 43.99% H 4.46% I 38.73% N 12.82% |
合成路线1
该中间体在本合成路线中的序号：(IV)The tetraimidazolyl porphyrin (III) was prepared by reaction between 1-ethylimidazole-2-carboxaldehyde (I) and pyrrole (II) in refluxing propionic acid. Quaternization of the imidazole groups of (III) with iodoethane furnished the tetrakis-imidazolium iodide salt (IV). After complexation of porphyrin (IV) with manganese(III) acetate, its precipitation as the hexafluorophosphate salt followed by anion exchange with tetrabutylammonium chloride, furnished the title chelate pentachloride salt.
| 【1】 Trova, M.P.; Kitchen, D.B.; Crapo, J.D.; Gauuan, P.J.F.; Day, B.J. (National Jewish Medical and Research Center); Substd. porphyrins. EP 1155019; JP 2002535332; WO 0043395 . |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 58657 | 1-ethyl-1H-imidazole-2-carbaldehyde | C6H8N2O | 详情 | 详情 | |
| (II) | 21674 | 1H-pyrrole | 109-97-7 | C4H5N | 详情 | 详情 |
| (III) | 58658 | 2,7,12,17-tetrakis(1-ethyl-1H-imidazol-2-yl)-21,22,23,24-tetraazapentacyclo[16.2.1.1~3,6~.1~8,11~.1~13,16~]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaene | C40H38N12 | 详情 | 详情 | |
| (IV) | 58659 | 1,3-diethyl-2-[7,12,17-tris(1,3-diethyl-1H-imidazol-3-ium-2-yl)-21,22,23,24-tetraazapentacyclo[16.2.1.1~3,6~.1~8,11~.1~13,16~]tetracosa-1,3,5,7,9,11(23),12,14,16,18(21),19-undecaen-2-yl]-1H-imidazol-3-ium tetraiodide | C48H58I4N12 | 详情 | 详情 |