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【结 构 式】 
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【分子编号】56355 【品名】(4R)-5-amino-4-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid 【CA登记号】 |
【 分 子 式 】C8H15N3O4 【 分 子 量 】217.22492 【元素组成】C 44.23% H 6.96% N 19.34% O 29.46% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(XXXVII)A more direct procedure was based on the activation of the unprotected disaccharide acid (XXXVI) as the pentafluorophenyl ester (XXXVII) by treatment with bis(pentafluorophenyl) carbonate. Active ester (XXXVII) was subsequently coupled with L-alanyl-D-isoglutamine (XXXVIII) to afford the corresponding amide.
| 【1】 Andronova, T.M.; et al.; Bacterial cell wall glycopeptides as adjuvants. Colloq INSERM 1989, 174, 561. |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (XXXVI) | 56354 | 2,3,4,5,6-pentafluorophenyl (2R)-2-{[(3R,4R,5S,6R)-3-(acetylamino)-5-{[(2S,3R,4R,5S,6R)-3-(acetylamino)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2-hydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}propanoate | C25H31F5N2O13 | 详情 | 详情 | |
| (XXXVII) | 56355 | (4R)-5-amino-4-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid | C8H15N3O4 | 详情 | 详情 | |
| (XXXVIII) | 56356 | (2R,3S,4R,5R,6S)-3-(acetyloxy)-2-[(acetyloxy)methyl]-6-chloro-5-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)tetrahydro-2H-pyran-4-yl acetate | C20H20ClNO9 | 详情 | 详情 |
Extended Information