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【结 构 式】 
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【分子编号】56317 【品名】2-(alpha,alpha,alpha-Trifluoro-m-toluidino)nicotinic acid; 2-3-(Trifluoromethyl)anilinonicotinic acid; Niflumic acid 【CA登记号】4394-00-7 |
【 分 子 式 】C13H9F3N2O2 【 分 子 量 】282.2219496 【元素组成】C 55.33% H 3.21% F 20.2% N 9.93% O 11.34% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)The title morpholinoethyl ester was prepared by reaction of niflumic acid (I) with N-(2-chloroethyl)morpholine (II) in refluxing isopropanol.
| 【1】 Hoffmann, C. (Hexachimie SA); 2-Anilino-nicotinic acid esters. US 3708481 . |
Extended Information