sodium 3-sulfobenzoate -Drug Synthesis Database

【结构式】

【分子编号】59292

【品名】sodium 3-sulfobenzoate

【CA登记号】

【分子式】C₇H₅NaO₅S

【分子量】224.169468

【元素组成】C 37.51% H 2.25% Na 10.26% O 35.69% S 14.3%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(II)

Alternatively, the title compound is prepared by condensation of prednisolone 21-methanesulfonate (I) with sodium 3-sulfobenzoate (II) in DMF/H2O, followed by conversion to the corresponding sodium salt with aqueous sodium acetate.

参考文献中间体

合成目标

【1】 Joly, R.; Warnant, J. (Aventis Pharma SA); Novel process for the preparation of 21-esters of 20-keto-steroids. FR 1344153; US 3037034 .

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	14174	2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl methanesulfonate	35410-28-7	C₂₂H₃₀O₇S	详情	详情
(II)	59292	sodium 3-sulfobenzoate		C₇H₅NaO₅S	详情	详情

Extended Information