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【结 构 式】

【分子编号】53942

【品名】Suberic acid dichloride; Suberoyl chloride; Suberoyl dichloride

【CA登记号】10027-07-3

【 分 子 式 】C8H12Cl2O2

【 分 子 量 】211.08748

【元素组成】C 45.52% H 5.73% Cl 33.59% O 15.16%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(I)

1. A mixture of diacid dichloride (I), aniline (II), hydroxylamine (III) and KOH in 50% THF/water gives, after chromatographic purification, the title product with yields of 15-30%.

1 Breslow, R.; Rifkind, R.A.; Jursic, B. (Columbia University; Sloan-Kettering Institute); Novel potent inducers of terminal differentiation and methods of use thereof. WO 9307148 .
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 53942 Suberic acid dichloride; Suberoyl chloride; Suberoyl dichloride 10027-07-3 C8H12Cl2O2 详情 详情
(II) 12294 Aniline; Phenylamine 62-53-3 C6H7N 详情 详情
(III) 32201 Hydroxylamine 7803-49-8 H3NO 详情 详情
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