【结 构 式】 |
【分子编号】52485 【品名】 【CA登记号】 |
【 分 子 式 】C50H68N12O17 【 分 子 量 】1109.1606 【元素组成】C 54.14% H 6.18% N 15.15% O 24.52% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号:(XVIII)Basic hydrolysis of the methyl ester group of (XVII) and subsequent acidic cleavage of the tert-butyl esters gave rise to the hexacarboxylic acid derivative (XVIII). Finally, complexation of (XVIII) with 177LuCl3 furnished the title lutetium complex.
【1】 Cheesman, E.H.; et al.; Nonpeptide vitronectin antagonists labeled with Tc99m for imaging tumors. 222nd ACS Natl Meet (Aug 26 2001, Chicago) 2001, Abst MEDI 77. |
【2】 Sworin, M.; Cheesman, E.H.; Rajopadhyem, M. (DuPont Pharmaceuticals Co.); Vitronectin receptor antagonist pharmaceuticals. EP 1140864; WO 0035887 . |
Extended Information