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【结 构 式】

【分子编号】52485

【品名】 

【CA登记号】

【 分 子 式 】C50H68N12O17

【 分 子 量 】1109.1606

【元素组成】C 54.14% H 6.18% N 15.15% O 24.52%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(XVIII)

Basic hydrolysis of the methyl ester group of (XVII) and subsequent acidic cleavage of the tert-butyl esters gave rise to the hexacarboxylic acid derivative (XVIII). Finally, complexation of (XVIII) with 177LuCl3 furnished the title lutetium complex.

1 Cheesman, E.H.; et al.; Nonpeptide vitronectin antagonists labeled with Tc99m for imaging tumors. 222nd ACS Natl Meet (Aug 26 2001, Chicago) 2001, Abst MEDI 77.
2 Sworin, M.; Cheesman, E.H.; Rajopadhyem, M. (DuPont Pharmaceuticals Co.); Vitronectin receptor antagonist pharmaceuticals. EP 1140864; WO 0035887 .
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(XVII) 52484   C71H110N12O17 详情 详情
(XVIII) 52485   C50H68N12O17 详情 详情
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