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【结 构 式】 
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【分子编号】52311 【品名】 【CA登记号】 |
【 分 子 式 】C15H11N5O6Pt 【 分 子 量 】552.36244 【元素组成】C 32.62% H 2.01% N 12.68% O 17.38% Pt 35.32% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(IV)The exchange reaction of (1,5-cyclooctadiene)diiodoplatinum (I) with silver nitrate produced the platinum nitrate derivative (II). Complexation of (II) with 2,2':6',2''-terpyridine (III) produced the terpyridine-platinum complex (IV), which was subsequently treated with thioacetamide (V) to furnish the title compound.
| 【1】 Becker, K.; et al.; Human thioredoxin reductase is efficently inhibited by (2,2':6',2''-terpyridine)platinum(II) complexes. Possible implications for a novel antitumor strategy. J Med Chem 2001, 44, 17, 2784. |
| 【2】 Lowe, G. (Isis Innovation Ltd.); Platinum(II) cpds.. EP 1155025; WO 0050431 . |
Extended Information