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【结 构 式】 
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【分子编号】50719 【品名】Efaroxan 【CA登记号】 |
【 分 子 式 】C13H16N2O 【 分 子 量 】216.28292 【元素组成】C 72.19% H 7.46% N 12.95% O 7.4% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)The title enantiomer was obtained by resolution of the racemic efaroxan (I) with (+)-dibenzoyl-D-tartaric acid to produce, after two recrystallizations from MeOH/Et2O, the desired pure diastereomeric salt, which was then liberated by treatment with K2CO3.
| 【1】 Chapleo, C.B.; Doxey, J.C.; Stillings, M.R. (Reckitt & Colman Pharmaceuticals); Imidazoline derivs.. WO 9205171 . |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (I) | 50719 | Efaroxan | C13H16N2O | 详情 | 详情 |
Extended Information