2-(allyl-2-methylanilino)-N,N-diethylbenzamide -Drug Synthesis Database

【结构式】

【分子编号】48671

【品名】2-(allyl-2-methylanilino)-N,N-diethylbenzamide

【CA登记号】

【分子式】C₂₁H₂₆N₂O

【分子量】322.45032

【元素组成】C 78.22% H 8.13% N 8.69% O 4.96%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(X)

Syntheses of intermediate (XI), 5-allyl-10,11-dihydro-5H-dibenz[b,f]azepin-10-one: Cyclization of 2-[N-allyl-N-(2-methylphenyl)amino]-N,N-dimethylbenzamide (IX) or 2-[N-allyl-N-(2-methylphenyl)amino]-N,N-diethylbenzamide (X) by means of LDA and TMEDA in THF.

参考文献中间体

合成目标

【1】 Lohse, O.; Kaufmann, D.; France, J.; Beutler, U.; Funfschilling, P.; Zaugg, W.; Furet, P.; New synthesis of oxcarbazepine via remote metalation of protected N-o-tolyl-anthranilamide derivatives. Tetrahedron Lett 2001, 42, 3, 385.

中间体序号	中间体编号	品名	分子式	供应商	用于合成
(IX)	48670	2-(allyl-2-methylanilino)-N,N-dimethylbenzamide	C₁₉H₂₂N₂O	详情	详情
(X)	48671	2-(allyl-2-methylanilino)-N,N-diethylbenzamide	C₂₁H₂₆N₂O	详情	详情
(XI)	48672	5-allyl-5,11-dihydro-10H-dibenzo[b,f]azepin-10-one	C₁₇H₁₅NO	详情	详情

Extended Information