[4-(tert-butyl)phenyl]-N-methylmethanamine; N-[4-(tert-butyl)benzyl]-N-methylamine -Drug Synthesis Database

【结构式】

【分子编号】40524

【品名】[4-(tert-butyl)phenyl]-N-methylmethanamine; N-[4-(tert-butyl)benzyl]-N-methylamine

【CA登记号】

【分子式】C₁₂H₁₉N

【分子量】177.2896

【元素组成】C 81.3% H 10.8% N 7.9%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(II)

By condensation of 1-(chloromethyl)naphthalene (I) with N-(4-tert-butylbenzyl)-N-methylamine (II) by means of sodium carbonate in hot DMF.

【1】 Maeda, T.; Koshikawa, S.; Yamamoto, T.; Sasaki, K.; Yokoo, M.; Amemiya, K.; Hashimoto, R.; Arika, T.; Takase, M. (Kaken Pharmaceutical Co., Ltd.); Amine derivs. and fungicides containing the same. US 5021458 .

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	27408	1-(Chloromethyl)naphthalene	86-52-2	C₁₁H₉Cl	详情	详情
(II)	40524	[4-(tert-butyl)phenyl]-N-methylmethanamine; N-[4-(tert-butyl)benzyl]-N-methylamine		C₁₂H₁₉N	详情	详情

Extended Information