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【结 构 式】 
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【分子编号】38143 【品名】 【CA登记号】 |
【 分 子 式 】C40H72O26 【 分 子 量 】968.99608 【元素组成】C 49.58% H 7.49% O 42.93% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(IV)Oligosaccharide (I) was peracetylated with Ac2O and KOAc, yielding ester (II). Condensation with decyl alcohol in the presence of SnCl4 produced glycoside (III), which was deacetylated with NaOMe in MeOH to give (IV). Sulfation was effected by means of sulfur trioxide-pyridine, followed by passage through an ion-exchange resin to furnish the corresponding sodium sulfate salt.
| 【1】 Nakashima, H.; Yamamoto, N.; Uryu, T.; Katsuraya, K.; Synthesis of sulfated oligosaccharide glycosides having high anti-HIV activity and the relationship between activity and chemical structure. Carbohydr Res 1999, 315, 3-4, 234. |
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