1-methylhexylamine; 2-heptanamine -Drug Synthesis Database

【结构式】

【分子编号】37944

【品名】1-methylhexylamine; 2-heptanamine

【CA登记号】123-82-0

【分子式】C₇H₁₇N

【分子量】115.21872

【元素组成】C 72.97% H 14.87% N 12.16%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(III)

For the synthesis of the optically pure (R)-enantiomer, racemic 2-heptylamine (III) was resolved by means of immobilized, recombinant Candida antarctica lipase. The required (R)-2-heptylamine (IV) was then converted to the title compound by sequential methylation and propargylation.

参考文献中间体

合成目标

【1】 Berry, M.D.; R-2HMP: An orally active agent combining independent antiapoptotic and MAO-B-inhibitory activities. CNS Drug Rev 1999, 5, 2, 105.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(III)	37944	1-methylhexylamine; 2-heptanamine	123-82-0	C₇H₁₇N	详情	详情
(IV)	37945	(2R)-2-heptanamine; (1R)-1-methylhexylamine	6240-90-0	C₇H₁₇N	详情	详情

Extended Information