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【结 构 式】 
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【分子编号】37943 【品名】2-bromoheptane 【CA登记号】1974-04-5 |
【 分 子 式 】C7H15Br 【 分 子 量 】179.1001 【元素组成】C 46.94% H 8.44% Br 44.61% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(II)The racemic compound was synthesized by alkylation of N-methylpropargylamine (I) with 2-bromoheptane (II) in refluxing EtOH, followed by conversion to the corresponding hydrochloride salt.
| 【1】 Yu, P.H.; Davis, B.A.; Boulton, A.A. (University of Saskatchewan); Aliphatic propargylamines as selective MAO-B inhibitors and as neuroprotective agents. JP 1994505241; US 5169868; WO 9215551 . |
| 【2】 Yu, P.H.; et al.; Aliphatic propargylamines: Potent, selective, irreversible monoamine oxidase B inhibitors. J Med Chem 1992, 35, 20, 3705. |
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