(5S)-3-acetyl-4-hydroxy-5-methyl-2(5H)-furanone -Drug Synthesis Database

【结构式】

【分子编号】32018

【品名】(5S)-3-acetyl-4-hydroxy-5-methyl-2(5H)-furanone

【CA登记号】

【分子式】C₇H₈O₄

【分子量】156.13812

【元素组成】C 53.85% H 5.16% O 40.99%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(II)

TRK-710 was synthesized by reaction of the platinum complex (I) with 3-acetyl-4-hydroxy-5(S)-methylfuran-2(5H)-one (II) by means of silver sulfate and barium hydroxide in water.

参考文献中间体

合成目标

【1】 Kawai, H.; et al.; Synthesis and platinum complexes containing 3-acyltetronic acid derivatives as ligand and its antitumor activity. Symp Med Chem 1999, Abst 2P-21.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	23063	(R,R)-Cyclohexane-1,2-diamine dichloro platinum complex		C₆H₁₄Cl₂N₂Pt	详情	详情
(II)	32018	(5S)-3-acetyl-4-hydroxy-5-methyl-2(5H)-furanone		C₇H₈O₄	详情	详情

Extended Information