3-(1,1-dimethylheptyl)-1-hydroxy-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-benzo[c]chromen-9-one -Drug Synthesis Database

【结构式】

【分子编号】31569

【品名】3-(1,1-dimethylheptyl)-1-hydroxy-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-benzo[c]chromen-9-one

【CA登记号】

【分子式】C₂₄H₃₆O₃

【分子量】372.54804

【元素组成】C 77.38% H 9.74% O 12.88%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(I)

Nabilone (I) was converted to the methylene analogue (II). Then, methylation of phenol group provided the title compound.

【1】 Tremblay, N.; Labelle, M.; Rochette, C.; Dufresne, C.; Gallant, M.; Gareau, Y.; Metters, K.M.; Sawyer, N.; Slipetz, D.M.; Weech, P.K.; Structure activity relatioships of tetrahydrocannabibol analogues on human cannabinoid receptors. Bioorg Med Chem Lett 1996, 6, 2, 189.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	31569	3-(1,1-dimethylheptyl)-1-hydroxy-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-benzo[c]chromen-9-one		C₂₄H₃₆O₃	详情	详情
(II)	31570	3-(1,1-dimethylheptyl)-6,6-dimethyl-9-methylene-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-1-ol		C₂₅H₃₈O₂	详情	详情

Extended Information