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【结 构 式】

【分子编号】28177

【品名】1,2,3,4-tetrahydro-10-acridiniumolate

【CA登记号】

【 分 子 式 】C13H13NO

【 分 子 量 】199.25236

【元素组成】C 78.36% H 6.58% N 7.03% O 8.03%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(III)

By nitration of acridine N-oxide (III) with H2SO4 - HNO3 to the corresponding 9-nitroacridine N-oxide (IV), followed by reduction with Fe - acetic acid.

1 Klimov, G.A.; Makareva, T.N.; Tilichenko, M.N.; Shepetova, N.M.; Process for preparing substituted lactones of 2-(2'-hydroxyethyl)nicotinic acid or their N-oxides. SU 463323 .
2 Castaner, R.M.; Serradell, M.N.; Castaner, J.; Tacrine. Drugs Fut 1987, 12, 11, 1032.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(III) 28177 1,2,3,4-tetrahydro-10-acridiniumolate C13H13NO 详情 详情
(IV) 28178 9-nitro-1,2,3,4-tetrahydro-10-acridiniumolate C13H12N2O3 详情 详情
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