• English
  • 简体中文
Login Register
Current Location: Home > Feedback Help Print

【结 构 式】

【分子编号】27333

【品名】2-methoxy-5-[methyl(methylsulfonyl)amino]-N-(tetrahydro-3-furanylmethyl)benzamide

【CA登记号】

【 分 子 式 】C15H22N2O5S

【 分 子 量 】342.41616

【元素组成】C 52.62% H 6.48% N 8.18% O 23.36% S 9.36%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号:(II)

2-Methoxy-5-(N-methylmethanesulfonamido)-N-tetrahydrofurfurylbenzamide (II), which is prepared from (I) and tetrahydrofurfurylamine, is treated with SOCl2 in dichloroethane to give the dichloro compound (III). Treatment of (III) with EtNH2 gives title compound.

1 Masaru, O.; Hiroshi, M. (Shionogi & Co. Ltd.); Meta-sulfonamido-benzamides. DE 2803651; ES 466366; FR 2378758; GB 1557019; US 4328155; US 4328344; US 4330472; US 4350635; US 4351770; US 44313663 .
2 Ogata, M.; 710723-S. Drugs Fut 1985, 10, 9, 758.
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 27331 2-methoxy-5-[methyl(methylsulfonyl)amino]benzoic acid C10H13NO5S 详情 详情
(II) 27333 2-methoxy-5-[methyl(methylsulfonyl)amino]-N-(tetrahydro-3-furanylmethyl)benzamide C15H22N2O5S 详情 详情
(III) 27334 N-(2,5-dichloropentyl)-2-methoxy-5-[methyl(methylsulfonyl)amino]benzamide C15H22Cl2N2O4S 详情 详情
(IV) 27335 Tetrahydro-2-furanylmethanamine; Tetrahydrofurfurylamine 4795-29-3 C5H11NO 详情 详情
(V) 10928 Ethanamine 75-04-7 C2H7N 详情 详情
Extended Information