1,3-dipropyl-8-tricyclo[3.3.1.0(3,7)]non-3-yl-3,7-dihydro-1H-purine-2,6-dione -Drug Synthesis Database

【结构式】

【分子编号】20552

【品名】1,3-dipropyl-8-tricyclo[3.3.1.0(3,7)]non-3-yl-3,7-dihydro-1H-purine-2,6-dione

【CA登记号】

【分子式】C₂₀H₂₈N₄O₂

【分子量】356.46808

【元素组成】C 67.39% H 7.92% N 15.72% O 8.98%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(XII)

The selective biological hydroxylation of compounds (XII) by means of Absidia ramosa FERM BP-4605 in corn steep liquor, glucose, Brig 35 at 28 C, 5-7 days gives metabolites M1.

参考文献中间体

合成目标

【1】 Shimada, J.; Eguchi, T.; Yasuzawa, T.; Nakamura, A.; Horiguchi, A.; Mochida, K.; Suzuki, F.; Synthesis of rat metabolites of a adenosine A1 antagonist, KW-3902. Symp Med Chem 1996, Abst 1-P-24.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
M1	63837	8-(9-hydroxytricyclo[3.3.1.0~3,7~]non-3-yl)-1,3-dipropyl-3,7-dihydro-1H-purine-2,6-dione		C₂₀H₂₈N₄O₃	详情	详情
(XII)	20552	1,3-dipropyl-8-tricyclo[3.3.1.0(3,7)]non-3-yl-3,7-dihydro-1H-purine-2,6-dione		C₂₀H₂₈N₄O₂	详情	详情

Extended Information