(3R,4S,5S)-5-(2,6-dichloro-9H-purin-9-yl)-4-fluorotetrahydrofuran-2,3-diyl dibenzoate -Drug Synthesis Database

【结构式】

【分子编号】66208

【品名】(3R,4S,5S)-5-(2,6-dichloro-9H-purin-9-yl)-4-fluorotetrahydrofuran-2,3-diyl dibenzoate

【CA登记号】　

【分子式】C₂₃H₁₅Cl₂FN₄O₅

【分子量】517.3

【元素组成】C 53.40% H 2.92% Cl 13.71% F 3.67% N 10.83% O 15.46%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(III)

【1】 Montgomery JA,Fowler AT,et al.2001.Improved methods for synthesizing 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine. W02001060383

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	66206	(2R,3R,4S)-5-bromo-4-fluorotetrahydrofuran-2,3-diyl dibenzoate		C₁₈H₁₄BrFO₅	详情	详情
(II)	25254	2,6-dichloro-9H-purine	5451-40-1	C₅H₂Cl₂N₄	详情	详情
(III)	66208	(3R,4S,5S)-5-(2,6-dichloro-9H-purin-9-yl)-4-fluorotetrahydrofuran-2,3-diyl dibenzoate		C₂₃H₁₅Cl₂FN₄O₅	详情	详情
(IV)	63942	(2R,3R,4S,5R)-5-(2-chloro-6-methoxy-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydro-3-furanol		C₁₁H₁₂ClFN₄O₄	详情	详情

Extended Information