Bamet-R2, -Drug Synthesis Database

【结构式】

【药物名称】Bamet-R2

【化学名称】cis-Diamminechloro[N-[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxycholan-24-yl]glycinato-kappaO]platinum

【CA登记号】191595-91-2

【分子式】C₂₆H₄₈ClN₃O₆Pt

【分子量】729.23196

【开发单位】Universidad de Salamanca (Originator)

【药理作用】ONCOLYTIC DRUGS, Platinum Complexes

合成路线1

The title compound was obtained by mixing aqueous solutions of sodium cholylglycinate (I) and cis-diamminedichloroplatinum (II) at 80 C.

【1】 Criado, J.J.; et al.; Synthesis and characterization of the new cytostatic complex cis-diammineplatinum(II)-chlorocholylglycinate. Bioconjugate Chem 1997, 8, 4, 453.

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(I)	51697	sodium 2-([(4R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,17R)-3,7,12-trihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino)acetate		C₂₆H₄₂NNaO₆	详情	详情
(II)	51698	dichloroplatinum diammoniate		H₆Cl₂N₂Pt	详情	详情

Extended Information