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【结 构 式】

【药物名称】AF-2785

【化学名称】3-[1-(2,4-Dichlorobenzyl)-1H-indazol-3-yl]-2(E)-propenoic acid

【CA登记号】252025-48-2

【 分 子 式 】C17H12Cl2N2O2

【 分 子 量 】347.20339

【开发单位】Angelini (Originator)

【药理作用】Contraceptives, Disorders of Sexual Function and Reproduction, Treatment of, ENDOCRINE DRUGS, Male Contraceptives, CFTR Channel Inhibitors

合成路线1

The described compound can be obtained by treatment of carboxaldehyde (I) with potassium acetate (II) and acetic anhydride.

1 Cheng, C.Y.; Silvestrini, B. (Angelini Pharmaceuticals Inc.); 3-Substd. 1-benzyl-1H-indazole derivs. as antifertility agents. US 6001865 .
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 45929 1-(2,4-dichlorobenzyl)-1H-indazole-3-carbaldehyde C15H10Cl2N2O 详情 详情
(II) 44564 potassium acetate 127-08-2 C2H3KO2 详情 详情
Extended Information