(S)-7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl benzoate -Drug Synthesis Database

【结构式】

【分子编号】67462

【品名】(S)-7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl benzoate

【CA登记号】　

【分子式】C₃₃H₂₉ClN₂O₄

【分子量】553.057

【元素组成】C 71.67% H 5.28% Cl 6.41% N 5.06% O 11.57%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(III)

【1】 Yamashita H, Ohtani T, Morita S, et al.2002.Practical synthesis of both enantiomers of vasopressin V2 receptor antagonist OPC-41061 using the catalytic asymmetric hydrogenation, Heterocycles, 56: 123～128.

中间体序号	中间体编号	品名	分子式	供应商	用于合成
(I)	33008	N-[4-[(7-chloro-5-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl)carbonyl]-3-methylphenyl]-2-methylbenzamide	C₂₆H₂₃ClN₂O₃	详情	详情
(II)	67461	(S)-N-(4-(7-chloro-5-hydroxy-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)-3-methylphenyl)-2-methylbenzamide	C₂₆H₂₅ClN₂O₃	详情	详情
(III)	67462	(S)-7-chloro-1-(2-methyl-4-(2-methylbenzamido)benzoyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl benzoate	C₃₃H₂₉ClN₂O₄	详情	详情

Extended Information