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【结 构 式】 
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【分子编号】66843 【品名】2-(tert-butylamino)acetyl chloride hydrochloride 【CA登记号】 |
【 分 子 式 】C6H12ClNO.HCl 【 分 子 量 】186.081 【元素组成】C 38.73% H 7.04% Cl 38.10% N 7.53% O 8.60% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(V)
| 【1】 Krishnan L, Sum PE, Daigneault S, et aL. 2006. Process for the prepantion of tigecycline and methods of preparing 9-aminominocycline. W0 2006130500 |
| 【2】 Krishnan L, Sum PE, Daigneault S, et al. 2006. Preparation of tigecycline and 9-nitrominocycline. W0 2006130501 |
| 中间体序号 | 中间体编号 | 品名 | CAS号 | 分子式 | 供应商 | 用于合成 |
|---|---|---|---|---|---|---|
| (IX) | 66846 | (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide hydrochloride | C23H28N4O7.HCl | 详情 | 详情 | |
| (I) | 17895 | 2-Amino-2-methylpropane; tert-butylamine; 2-methyl-2-propanamine | 75-64-9 | C4H11N | 详情 | 详情 |
| (II) | 17430 | 2-Bromoacetic acid tert-butyl ester; tert-butyl 2-bromoacetate; tert-Butyl bromoacetate | 5292-43-3 | C6H11BrO2 | 详情 | 详情 |
| (III) | 66841 | tert-butyl 2-(tert-butylamino)acetate | C10H21NO2 | 详情 | 详情 | |
| (IV) | 66842 | 2-(tert-butylamino)acetic acid hydrochloride | C6H13NO2.HCl | 详情 | 详情 | |
| (V) | 66843 | 2-(tert-butylamino)acetyl chloride hydrochloride | C6H12ClNO.HCl | 详情 | 详情 | |
| (VI) | 65813 | Minocycline hydrochloride; [4S-(4alpha,4aalpha,5aalpha,12aalpha)]-4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide monohydrochloride | 13614-98-7 | C23H27N3O7.HCl | 详情 | 详情 |
| (VII) | 66844 | (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-9-nitro-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide monosulfate | C23H26N4O9.2H2SO4 | 详情 | 详情 | |
| (VIII) | 66845 | (4S,4aS,5aR,12aS)-9-amino-4,7-bis(dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-naphthacenecarboxamide monosulfate | C23H28N4O7.2H2SO4 | 详情 | 详情 |
Extended Information