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【结 构 式】 
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【分子编号】61405 【品名】6-Amino-1,1-dioxobenzo[b]thiophene, tech. 【CA登记号】 |
【 分 子 式 】C8H7NO2S 【 分 子 量 】181.21512 【元素组成】C 53.02% H 3.89% N 7.73% O 17.66% S 17.69% |
与该中间体有关的原料药合成路线共 1 条
合成路线1
该中间体在本合成路线中的序号：(I)Diazotization of 5-aminobenzo[b]thiophene 1,1-dioxide (I), followed by treatment with sulfur dioxide and cupric chloride gives rise to the sulfonyl chloride (II). Subsequent condensation of acid chloride (II) with butylamine (III) produces the corresponding sulfonamide.
| 【1】 Villar, R.; et al.; New hydrophobic benzo[b]thiophenesulfonamide 1,1-dioxide as potential antineoplastic agents. Drugs Fut 2002, 27, Suppl. A. |
Extended Information