2-({(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl}amino)-1-ethanesulfonic acid -Drug Synthesis Database

【结构式】

【分子编号】59141

【品名】2-({(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl}amino)-1-ethanesulfonic acid

【CA登记号】

【分子式】C₂₆H₄₅NO₅S

【分子量】483.71304

【元素组成】C 64.56% H 9.38% N 2.9% O 16.54% S 6.63%

与该中间体有关的原料药合成路线共 1 条

合成路线1

该中间体在本合成路线中的序号：(VIII)

A further method was based on the microbial hydroxylation of taurolithocholic acid (VIII) by the action of a microorganism belonging to the Mortierella genus.

参考文献中间体

合成目标

【1】 Sawada, H.; Watanuki, M. (Yakult Honsha Co., Ltd.); Procuding conjugated ursodeoxycholic acids. EP 0119040 .

中间体序号	中间体编号	品名	CAS号	分子式	供应商	用于合成
(VIII)	59141	2-({(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl}amino)-1-ethanesulfonic acid		C₂₆H₄₅NO₅S	详情	详情

Extended Information