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【结 构 式】 
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【药物名称】T-0070907 【化学名称】2-Chloro-5-nitro-N-(4-pyridyl)benzamide 【CA登记号】313516-66-4, 372095-17-5 (hydrochloride) 【 分 子 式 】C12H8ClN3O3 【 分 子 量 】277.66886 |
【开发单位】Sankyo (Originator), Tularik (Codevelopment) 【药理作用】Antidiabetic Drugs, Antiobesity Drugs, ENDOCRINE DRUGS, METABOLIC DRUGS, Treatment of Nutritional Disorders, PPARgamma Antagonists |
合成路线1
The title carboxamide is prepared by coupling 2-chloro-5-nitrobenzoyl chloride (I) with 4-aminopyridine (II) in DMA
| 【1】 Amemiya, Y.; Wakabayashi, K.; Takaishi, S.; Fukuda, C. (Sankyo Co., Ltd.); PPARgamma modulators. EP 1277729; JP 2002332266; WO 0183427 . |
Extended Information