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【结 构 式】 
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【药物名称】N20C 【化学名称】N2-(3,3-Diphenylpropyl)glycinamide 【CA登记号】76991-05-4 【 分 子 式 】C17H20N2O 【 分 子 量 】268.36175 |
【开发单位】CSIC (Originator), Fundación Valenciana Invest Biomédicas (Originator), Universidad de Extremadura (Originator), Universidad de Valencia (Originator), Universidad Miguel Hernandez (Originator) 【药理作用】Cerebrovascular Diseases, Treatment of, NEUROLOGIC DRUGS, ONCOLYTIC DRUGS, Stroke, Treatment of, NMDA Antagonists |
合成路线1
The title compound is prepared by alkylation of 3,3-diphenylpropylamine (I) with bromoacetamide (II) in the presence of K2CO3 in acetonitrile (1).
| 【1】 Ognyanov, V.I.; Borden, L.; Bell, S.C.; Zhang, J. (NPS Allelix Corp.); Pharmaceutical for treatment of neurological and neuropsychiatric disorders. EP 1014966; JP 2002515037; US 6191165; WO 9745115 . |
Extended Information