合成路线1

The chiral amino alcohol (I) is acylated with octanoic acid (II), using EDC and HOBt, to afford amide (III). The lithium alkoxide of (III) is then phosphorylated by dibenzyl phosphorochloridate, yielding phosphate ester (IV). Benzyl groups cleavage in (IV) is effected by catalytic hydrogenation of (IV) over Pd/C to produce acid (V), which is finally converted to the title disodium salt by treatment with NaOH in EtOH.