【结 构 式】 |
【药物名称】Methypranolol, Metipranolol, VUFB-6453, VUAB-6453, BMOI-004, Turoptin, Betanol, Minims metipranolol, Optipranolol 【化学名称】Acetic acid 4-[2-hydroxy-3-(isopropylamino)propoxy]-2,3,6-trimethylphenyl ester 【CA登记号】22664-55-7 【 分 子 式 】C17H27NO4 【 分 子 量 】309.40904 |
【开发单位】Bausch & Lomb (Originator), Chauvin (Originator), Novartis Ophthalmics (Not Determined) 【药理作用】Antiglaucoma Agents, OCULAR MEDICATIONS, Ophthalmic Drugs |
合成路线1
The condensation of the epoxide (I) with isopropylamine (II) gives the target isopropanol derivative.
【1】 Zolss, G.; Pfarrhofer, G. (Aventis Pharma AG); Novel crystalline salts of aryloxy-propanolamines, a process for their preparation and their use. DE 3544172; EP 0229947; US 4767784 . |
Extended Information