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【结 构 式】 
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【药物名称】ZSET-845 【化学名称】3,3-Dibenzylimidazo[1,2-a]pyridin-2(3H)-one 【CA登记号】324077-62-5 【 分 子 式 】C21H18N2O 【 分 子 量 】314.39041 |
【开发单位】Zenyaku Kogyo (Originator) 【药理作用】Alzheimer's Dementia, Treatment of , Antiparkinsonian Drugs, Cognition Disorders, Treatment of, Extrapyramidal Disorders, Treatment of, NEUROLOGIC DRUGS, Senile Dementia, Treatment of |
合成路线1
The cyclization of 2-amino-1-(ethoxycarbonylmethyl)pyridinium bromide (I) with benzyl bromide (II) by means of sodium ethoxide in ethanol gives the target imidazopyridinone derivative.
| 【1】 Saitoh, K.; Fukuda, N.; Matsuno, T.; Yamaguchi, Y.; Kawashima, S.; Higashi, M. (Zenyaku Kogyo Co., Ltd.); Azaindolizinone derivs. and cerebral function improvers containing the same as the active ingredient. EP 1219621; WO 0109131 . |
Extended Information