|
【结 构 式】 
|
【药物名称】 【化学名称】2-Cyano-2-(3-methyl-3H-imidazo[4,5-b]pyridin-2-yl)-N-(4-methylphenyl)thioacetamide 【CA登记号】 【 分 子 式 】C17H15N5S 【 分 子 量 】321.4066 |
【开发单位】Medical University of Gdansk (Originator) 【药理作用】ANTIINFECTIVE THERAPY, Antimycobacterial Agents, Treatment of Tuberculosis |
合成路线1
The title thioamide was prepared by condensation of the known 2-cyanomethyl-3-methyl-3H-imidazo[4,5-b]pyridine (I) with 4-tolyl isothiocyanate (II) in the presence of KOH.
| 【1】 Bukowski, L.; Some reactions of 2-cyanomethyl-3-methyl-3H-imidazo[4,5-b]pyridine with isothiocyanates. Antituberculotic activity of the obtained compounds. Pharmazie 2001, 56, 1, 23. |
Extended Information