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【结 构 式】 
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【药物名称】 【化学名称】1,5-Bis(4-hydroxy-2,3,5-trimethylphenoxy)pentane 【CA登记号】 【 分 子 式 】C23H32O4 【 分 子 量 】372.50909 |
【开发单位】Tokushima Bunri University (Originator) 【药理作用】Antiallergy/Antiasthmatic Drugs, Asthma Therapy, ONCOLYTIC DRUGS, RESPIRATORY DRUGS, Antioxidants, Lipoxygenase Inhibitors |
合成路线1
The target product can be obtained by condensation of trimethylhydroquinone (I) with diol (II) by means of phosphomolybdic acid in refluxing toluene followed by recrystallization from n-hexane/ethyl acetate.
| 【1】 Satoh, T.; Miyataka, H.; Nishiki, M.; Hirano, T.; Kawasaki, N.; Antioxidative and 5-lipoxygenase inhibiting activities of novel bis(4-hydroxy-2,3,5-trimethylphenoxy)alkyl derivatives. Chem Pharm Bull 2001, 49, 2, 225. |
Extended Information