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【结 构 式】 
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【药物名称】91-454 【化学名称】2-Cyano-3-(3-methoxyphenyl)-2(Z)-propenoic acid ethyl ester 【CA登记号】19098-69-2 (undefined isomer) 【 分 子 式 】C13H13NO3 【 分 子 量 】231.25346 |
【开发单位】Central Drug Research Institute (Originator) 【药理作用】ANTIINFECTIVE THERAPY, Antileishmanials, Treatment of Protozoal Diseases |
合成路线1
By condensation of 3-methoxybenzaldehyde (I) with ethyl cyanoacetate (II) by means of NaOH in ethanol.
| 【1】 Tiwari, S.; et al.; Synthesis and antileishmanial activity of alpha-cyano ethyl propenoates - A new class of antileishmanials. Arzneim-Forsch Drug Res 1999, 49, 2, 144. |
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