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【结 构 式】

【药物名称】D-7193 (as di-L-lysine salt), D-7042, H-327/86

【化学名称】N,N'-Diacetyl-L-cystine

【CA登记号】139602-29-2

【 分 子 式 】C10H16N2O6S2

【 分 子 量 】324.37682

【开发单位】AstraZeneca (Originator)

【药理作用】Atherosclerosis Therapy, CARDIOVASCULAR DRUGS, IMMUNOMODULATING AGENTS, Immunomodulators, Treatment of Disorders of the Coronary Arteries and Atherosclerosis

合成路线1

The title compound may be prepared either by acetylation of L-cystine (I) or by oxidative dimerization of N-acetylcysteine (II).

1 Andersson, C.-M.A.; Bergstrand, S.H.A.; Hallberg, A.R.; Särnstrand, B.O.; Tunek, P.A.S. (AstraZeneca plc); The pharmacological use of certain cystine derivs.. EP 0463514; EP 0532595; EP 0727207; JP 1992230359; JP 1993507705; US 5441976; US 5780508; WO 9118594 .
中间体序号 中间体编号 品名 CAS号 分子式 供应商 用于合成
(I) 42188 (2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propionic acid C6H12N2O4S2 详情 详情
(II) 39365 (2S)-2-(acetamido)-3-sulfanylpropionic acid 616-91-1 C5H9NO3S 详情 详情
Extended Information